Human Studies of Target Identification, Biomarkers and Disease Mechanisms Specific to CNS Small Blood and Lymphatic Vessels (R01)


Posted Date: September 18, 2017

Due Date: December 11, 2017

Budget: $499,999

The NIH Blueprint for Neuroscience Research is a collaborative framework through which 14 NIH Institutes, Centers and Offices jointly support neuroscience-related research, with the aim of accelerating discoveries and reducing the burden of nervous system disorders.

This Funding Opportunity Announcement (FOA) will solicit research projects to facilitate the development and translation of tools and technology for non-invasive imaging and profiling of human central nervous system (CNS, including retina) small blood and lymphatic vessels; to investigate their role in CNS physiology, disease, repair processes, and responses to therapy using novel approaches. Applications can be focused on the development of new technology and tools, novel target or biomarker identification and validation studies, or a combination of mechanistic and technology development studies specific to human CNS small blood and lymphatic vessels in health and disease, across the life span.

This initiative is one of the science projects supported by the NIH Blueprint for Neuroscience Research in FY 2018, which also include initiatives on “Dynamic Neuroimmune Interactions in the transition from Brain Function to Dysfunction” and “Characterization of Extracellular Vesicles.” For additional information on FOAs of NIH Blueprint science projects, please check NIH Blueprint website

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