Enhanced Career Development Award

Funder: Foundation Fighting Blindness

Due Date: January 21, 2018

Budget: $510,000


Background and Objective


The Foundation Fighting Blindness (FFB) and the Foundation Fighting Blindness-Clinical Research Institute (FFB-CRI) are dedicated to supporting research to advance therapeutic and preventive strategies for inherited orphan retinal degenerative diseases into the clinic.  Through the efforts of investigators supported by FFB and FFB-CRI, substantial advances have been made in our understanding of these diseases, including genetic determinants, cellular, molecular and genetic mechanisms, regenerative medicine, neuroprotection, and gene therapy strategies.  With this enhanced knowledge, new treatment and prevention strategies are being developed and can now be tested in the clinical setting.  In order to capitalize on current and emerging opportunities, FFB recognizes the importance of and need to ensure an adequate supply of clinical scientists.


This program for enhanced research and clinical training is intended to support a strong pool of clinician-scientists with a commitment to clinical research on inherited orphan retinal degenerative diseases by providing support for:

  • the recruitment of clinician-scientists whose research focus in iRDs has been for five or fewer years, or
  • the retention of early-career clinician-scientists with prior career development support (K-type or other CDA) who have not secured support as Principal Investigator for independent research (e.g. R01 or Individual Investigator award).


The Program will provide support and protected time to individuals with M.D. and M.D./Ph.D. degrees for career development in clinical research related to inherited orphan retinal degenerative diseases leading to research and clinical independence.


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