From Association to Function in the Alzheimers Disease Post-Genomics Era (R01 – Clinical Trial Not Allowed)

Funder: National Institutes of Health

Due Date: 3/28/2018

Budget: $3,500,000

Opportunity: RFA-AG-18-026

This Funding Opportunity Announcement (FOA) solicits innovative and collaborative research focused on understanding the structure and function of proteins or protein complexes regulated by different AD genetic variants that have been identified to be associated with the sporadic and late onset Alzheimer’s disease (AD). Specifically, NIA is interested in identifying and developing more effective and integrated platforms to screen protein functions, protein-protein interaction, protein complexes and their regulation by AD genetic variants prior to any in-depth mechanistic studies. The program encourages collaborative research projects that will translate initial GWAS discovery into functional and phenotypical insights and ultimately lead to understand the complex biology of AD.

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